Mammalian prions, the pathogens that cause transmissible spongiform encephalopathies, propagate by self-perpetuating the structural information stored in the abnormally folded, aggregated conformer (PrPSc) of the host-encoded prion protein (PrPC).To date, no structural model related to prion assembly organization satisfactorily describes how strain
The advent of AI and 5G technologies has markedly enhanced the intelligence and connectivity of UAVs, leading to the development of UAV swarms.These swarms not only exhibit superior efficiency and adaptability in collective tasks but also offer considerable potential in both civilian and military sectors.However, despite the innovative insights pro
The relationships between conformation traits and longevity traits were analyzed in 41 489 Holstein cows born in the years 1994-1999 which were culled by 30th June 2005.Pearson correlation coefficients between type traits and the herd life or productive life of cows were calculated.The effects of type trait scoring level on the length of productive
We have recently identified transcription factors (TFs) that are Saw Stands key drivers of breast cancer risk.To better understand the pathways or sub-networks in which these TFs mediate their function we sought to identify upstream modulators of their activity.We applied the MINDy (Modulator Inference by Network Dynamics) algorithm to four TFs (ES
The Western clawed frog, Xenopus tropicalis, is a highly promising model amphibian, especially in developmental and physiological research, and as a tool for understanding disease.It was originally found in the West African rainforest belt, and was introduced to the research community in the 1990s.The major strains thus far known include the Nigeri